The Cleveland Guardians travel to Baltimore for a Wednesday night regular season matchup against the Orioles, with first pitch scheduled for 6:35 PM ET at Oriole Park at Camden Yards. Foster Griffin takes the ball for Cleveland opposite Baltimore's Shane Baz in a game that carries real weight as September baseball heats up. The Guardians roll out a lineup anchored by José Ramírez at third base with Steven Kwan setting the table at the top. This one is available on WTAM 1100 and Guardians.TV Presented by Progressive for fans back in Cleveland.

Probable Starters: Foster Griffin vs. Shane Baz

Foster Griffin draws the start for the Guardians. The left-hander will need to navigate a Baltimore lineup that features real firepower, including Pete Alonso at the two-hole and Coby Mayo in the middle of the order as the designated hitter. Griffin's assignment is straightforward — keep the Orioles off the board long enough for Cleveland's offense to do its work.

Shane Baz gets the nod for Baltimore. The Orioles right-hander will be tested early by a Guardians lineup that has legitimate threats from top to bottom. Baz will need to be sharp against a Cleveland order that features Ramírez, Jo Adell hitting cleanup, and Travis Bazzana slotted fifth.

Cleveland Guardians Lineup at Baltimore

• 1. Steven Kwan, CF
• 2. Chase DeLauter, RF
• 3. José Ramírez, 3B
• 4. Jo Adell, LF
• 5. Travis Bazzana, DH
• 6. Nathaniel Lowe, 1B
• 7. Angel Genao, 2B
• 8. Patrick Bailey, C
• 9. Brayan Rocchio, SS

Baltimore Orioles Lineup

• 1. Dylan Beavers, LF
• 2. Pete Alonso, 1B
• 3. Coby Mayo, DH
• 4. Christian Encarnacion-Strand, 3B
• 5. Jackson Holliday, SS
• 6. Rece Hinds, CF
• 7. Jeremiah Jackson, 2B
• 8. Leody Taveras, RF
• 9. Carlos Narváez, C

Keys to Watch for Cleveland

• Ramírez as the engine: José Ramírez hitting third is as reliable an anchor as Cleveland has. How he performs against Baz will set the tone for the middle of this order.
• Griffin's command early: Getting into the fifth and sixth innings with Baltimore's lineup under control is the job. If Griffin commands the strike zone, this game stays manageable.
• Kwan on base: Steven Kwan leading off does exactly what Cleveland needs — get on base, create pressure, and let the heart of the order drive him home. His ability to work counts against Baz matters.
• Bazzana and Adell producing in the middle: With Adell at cleanup and Bazzana at five, Cleveland has the potential to string together big innings. Both need to deliver when opportunities arise.
• Alonso and Encarnacion-Strand for Baltimore: Pete Alonso at second and Christian Encarnacion-Strand at four give the Orioles legitimate middle-of-the-order punch. Griffin cannot give those two anything to drive.

Prediction

This figures to be a tight one. Griffin will need to be disciplined against a Baltimore lineup that has the capacity to put up a crooked number quickly, particularly with Alonso, Mayo, and Encarnacion-Strand sitting in the heart of their order. But Cleveland's lineup is built to grind, and Ramírez in September is always a dangerous proposition for opposing starters. If Kwan gets on base consistently and the middle of the Cleveland order stays productive, the Guardians have the pieces to come out of Camden Yards with a win. Guardians 4, Orioles 3.